Frontonasal process-specific disruption of AP-2α results in postnatal midfacial hypoplasia, vascular anomalies, and nasal cavity defects

• Published in: Developmental biology Vol. 267; no. 1; pp. 72 - 92
• Main Authors: Nelson, D.K, Williams, T
• Format: Journal Article
• Language: English
• Published: 01.03.2004

A majority of the bones of the vertebrate cranial vault and craniofacial complex develop via intramembranous ossification, and are separated by fibrous sutures that undergo osteogenic differentiation in response to growth stimuli. Craniosynostosis is a common human birth defect that results from the...