Assocation Between Leber's Hereditary Optic Neuropathy and MT-ND1 3460G>A Mutation-Induced Alterations in Mitochondrial Function, Apoptosis, and Mitophagy

• Published in: Investigative ophthalmology & visual science Vol. 62; no. 9; p. 38
• Main Authors: Zhang, Juanjuan, Ji, Yanchun, Chen, Jie, Xu, Man, Wang, Guoping, Ci, Xiaorui, Lin, Bing, Mo, Jun Q., Zhou, Xiangtian, Guan, Min-Xin
• Format: Journal Article
• Language: English
• Published: The Association for Research in Vision and Ophthalmology 01.07.2021
• Subjects: Biochemistry and Molecular Biology

To investigate the molecular mechanism underlying the Leber's hereditary optic neuropathy (LHON)-linked MT-ND1 3460G>A mutation.PurposeTo investigate the molecular mechanism underlying the Leber's hereditary optic neuropathy (LHON)-linked MT-ND1 3460G>A mutation.Cybrid cell models we...