Ferric Gluconate Is Highly Efficacious in Anemic Hemodialysis Patients with High Serum Ferritin and Low Transferrin Saturation Results of the Dialysis Patients’ Response to IV Iron with Elevated Ferritin (DRIVE) Study

• Published in: Journal of the American Society of Nephrology Vol. 18; no. 3; pp. 975 - 984
• Main Authors: Coyne, Daniel W., Kapoian, Toros, Suki, Wadi, Singh, Ajay K., Moran, John E., Dahl, Naomi V., Rizkala, Adel R.
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 01.03.2007
• Subjects: Anemia - drug therapy; Anemia - etiology; Anemias. Hemoglobinopathies; Biological and medical sciences; Diseases of red blood cells; Female; Ferric Compounds - administration & dosage; Ferric Compounds - adverse effects; Ferric Compounds - pharmacology; Ferritins - blood; Hematinics - administration & dosage; Hematinics - adverse effects; Hematinics - pharmacology; Hematologic and hematopoietic diseases; Hemoglobins - metabolism; Humans; Injections, Intravenous; Male; Medical sciences; Middle Aged; Nephrology. Urinary tract diseases; Renal Dialysis - adverse effects; Transferrin - analysis; High; Human; Transferrin; Nephrology; Anemia; Hemodialysis; Saturation; Ferritin; Hemopathy; Urology; Extrarenal dialysis; Low; Serum; Dialysis; Iron IV

Few data exist to guide treatment of anemic hemodialysis patients with high ferritin and low transferrin saturation (TSAT). The Dialysis Patients' Response to IV Iron with Elevated Ferritin (DRIVE) trial was designed to evaluate the efficacy of intravenous ferric gluconate in such patients. Inc...