Mechanisms of changes in nitrogen washout and lung volumes after saline infusion in humans

• Published in: The American review of respiratory disease Vol. 136; no. 4; p. 824
• Main Authors: Goeree, G W, Coates, G, Powles, A C, Basalygo, M
• Format: Journal Article
• Language: English
• Published: United States 01.10.1987
• Subjects: Adult; Airway Resistance - drug effects; Atropine - pharmacology; Blood Volume - drug effects; Erythrocytes - diagnostic imaging; Humans; Infusions, Intravenous; Lung - drug effects; Lung - physiology; Lung Volume Measurements - methods; Male; Middle Aged; Nitrogen - physiology; Radionuclide Imaging; Sodium Chloride - pharmacology; Technetium; Technetium Tc 99m Pyrophosphate; Time Factors; Tin Polyphosphates

This study was performed to determine the roles of increased intrathoracic blood volume and increased vagal tone in the changes in lung volume and nitrogen washout produced by saline infusion. In the first study, measurements of TLC, VC, FRC, ERV, and slope of phase III nitrogen washout (delta N2) w...