Interaction between Lipopolysaccharide (LPS), LPS-Binding Protein (LBP), and Planar Membranes

• Published in: Biological chemistry Vol. 382; no. 3; pp. 425 - 434
• Main Authors: Gutsmann, Thomas, Haberer, Niels, Carroll, Stephen F., Seydel, Ulrich, Wiese, Andre
• Format: Journal Article
• Language: English
• Published: Germany Walter de Gruyter 01.03.2001
• Subjects: Acute-Phase Proteins; Antibodies - metabolism; Carrier Proteins - chemistry; Carrier Proteins - immunology; Carrier Proteins - metabolism; Cell Membrane - chemistry; Cell Membrane - metabolism; Humans; Immune Sera; Lipid A - chemistry; Lipid A - immunology; Lipid A - metabolism; Lipid Bilayers - chemistry; Lipopolysaccharides - chemistry; Lipopolysaccharides - metabolism; Membrane Glycoproteins

The mechanism of interaction of the lipopolysaccharide (LPS)binding protein, LBP, with differently composed symmetric and asymmetric planar lipid bilayers was investigated in electrical measurements (membrane current, potential, capacitance). From a change of the inner membrane potential difference,...