F-actin flashes on phagosomes mechanically deform contents for efficient digestion in macrophages

The mechanism and role of transient F-actin recruitment, or F-actin 'flashes', on phagosomes remains enigmatic. Here we provide a comprehensive characterization of F-actin flashing dynamics on phagosomes, including receptor and signaling involvement. F-actin flashes predominate during the...

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Bibliographic Details
Published inJournal of cell science Vol. 133; no. 12
Main Authors Poirier, Mathieu B, Fiorino, Cara, Rajasekar, Thiviya K, Harrison, Rene E
Format Journal Article
LanguageEnglish
Published England 24.06.2020
Subjects
Complement
Macrophages
Phagocytosis
Phagosome maturation
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