MLKL deficiency elevates testosterone production in male mice independently of necroptotic functions

Mixed lineage kinase domain-like (MLKL) is a pseudokinase, best known for its role as the terminal effector of the necroptotic cell death pathway. MLKL-mediated necroptosis has long been linked to various age-related pathologies including neurodegeneration, atherosclerosis and male reproductive decl...

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Published inCell death & disease Vol. 15; no. 11; pp. 851 - 10
Main Authors Chiou, Shene, Cawthorne, Wayne, Soerianto, Thomas, Hofferek, Vinzenz, Patel, Komal M., Garnish, Sarah E., Tovey Crutchfield, Emma C., Hall, Cathrine, Hildebrand, Joanne M., McConville, Malcolm J., Lawlor, Kate E., Hawkins, Edwin D., Samson, Andre L., Murphy, James M.
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 21.11.2024
Springer Nature B.V
Nature Publishing Group
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