Use of protein electrophoresis in the diagnosis of cerebrospinal fluid rhinorrhoea

The diagnosis of CSF rhinorrhoea on clinical grounds alone can be difficult. We describe how the use of non-invasive electrophoretic analysis of nasal secretions for tau protein (asialotransferrin) helped in the management of cases where the existence of a CSF leak was in doubt. Patients were thus s...

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Published inJournal of laryngology and otology Vol. 106; no. 6; p. 504
Main Authors Porter, M J, Brookes, G B, Zeman, A Z, Keir, G
Format Journal Article
LanguageEnglish
Published England 01.06.1992
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Abstract The diagnosis of CSF rhinorrhoea on clinical grounds alone can be difficult. We describe how the use of non-invasive electrophoretic analysis of nasal secretions for tau protein (asialotransferrin) helped in the management of cases where the existence of a CSF leak was in doubt. Patients were thus saved unnecessary invasive investigations or surgery. A modification of the method of analysis, which improves diagnostic accuracy, is described.
AbstractList The diagnosis of CSF rhinorrhoea on clinical grounds alone can be difficult. We describe how the use of non-invasive electrophoretic analysis of nasal secretions for tau protein (asialotransferrin) helped in the management of cases where the existence of a CSF leak was in doubt. Patients were thus saved unnecessary invasive investigations or surgery. A modification of the method of analysis, which improves diagnostic accuracy, is described.
Author Brookes, G B
Keir, G
Zeman, A Z
Porter, M J
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Snippet The diagnosis of CSF rhinorrhoea on clinical grounds alone can be difficult. We describe how the use of non-invasive electrophoretic analysis of nasal...
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StartPage 504
SubjectTerms Adult
Cerebrospinal Fluid Proteins - analysis
Cerebrospinal Fluid Rhinorrhea - diagnosis
Electrophoresis, Agar Gel
Female
Humans
Male
tau Proteins - analysis
Title Use of protein electrophoresis in the diagnosis of cerebrospinal fluid rhinorrhoea
URI https://www.ncbi.nlm.nih.gov/pubmed/1624884
Volume 106
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