Environmental resistome–guided development of resistance-tolerant antibiotics - Peek, James; Bhattacharjee, Abir; Burian, Ján; Hsieh, David Chun-Cheng; Hernandez, Yozen; Ternei, Melinda; Panfil, Cecilia; Brady, Sean F. (Proceedings of the National Academy of Sciences - PNAS, 2025)
Keywords: Analogs; Anti-Bacterial Agents - chemistry; Anti-Bacterial Agents - pharmacology; Antibiotic resistance; Antibiotics; Bacteria - drug effects; Bacteria - genetics; Congeners; Drug Resistance, Bacterial - genetics; Lead compounds; Metagenome; Metagenomics; Metagenomics - methods; drug development; resistome; antibiotic resistance; metagenomics