Recent Advances of Oxidative Radical Cross‐Coupling Reactions: Direct α‐C(sp3)–H Bond Functionalization of Ethers and Alcohols

• Published in: Advanced synthesis & catalysis Vol. 359; no. 1; pp. 2 - 25
• Main Authors: Guo, Sheng‐rong, Kumar, Pailla Santhosh, Yang, Minghua
• Format: Journal Article
• Language: English
• Published: 04.01.2017
• Subjects: Alcohols; Bonding; C(sp3)–H bond functionalization; Carbon-carbon composites; Chemical reactions; Coupling; Ethers; radical oxidative coupling; Radicals; single eletron transfer (SET); Strategy

Oxygen‐containing heterocycles are an important class of compounds with diverse biological activities. In recent years, direct α‐C–H functionalization of inexpensive and abundant readily available ethers and alcohols by oxidative radical cross‐coupling with different nucleophilic partners (C–H, N–H,...