Serial Assessment of Gray Matter Abnormalities after Sport-Related Concussion

• Published in: Journal of neurotrauma Vol. 34; no. 22; pp. 3143 - 3152
• Main Authors: España, Lezlie Y., Lee, Ryan M., Ling, Josef M., Jeromin, Andreas, Mayer, Andrew R., Meier, Timothy B.
• Format: Journal Article
• Language: English
• Published: United States Mary Ann Liebert, Inc 15.11.2017
• Subjects: Adult; Amygdala; Amygdala - diagnostic imaging; Amygdala - pathology; Athletic Injuries - blood; Athletic Injuries - diagnostic imaging; Athletic Injuries - pathology; Biomarkers; Brain Concussion - blood; Brain Concussion - diagnostic imaging; Brain Concussion - pathology; Brain research; Cerebral Cortex - diagnostic imaging; Cerebral Cortex - pathology; Concussion; Cortex; Diffusion; Diffusion Tensor Imaging - methods; Female; Follow-Up Studies; Glial fibrillary acidic protein; Glial Fibrillary Acidic Protein - blood; Globus Pallidus - diagnostic imaging; Globus Pallidus - pathology; Gray Matter - diagnostic imaging; Gray Matter - pathology; Humans; Male; Medical imaging; Neurosciences; Neurosurgery; NMR; Nuclear magnetic resonance; Pediatrics; Physiology; Plasma levels; Proteins; Src protein; Substantia grisea; Traumatic brain injury; Young Adult; New Mexico; United States > US; Wisconsin; fractional anisotropy; diffusion; concussion; mTBI; GFAP

There is an urgent need to characterize the acute physiological effects of sport-related concussion (SRC). We investigated the effects of SRC on gray matter structure and diffusion metrics in collegiate athletes at 1.64 (T1; n = 33), 8.33 (T2; n = 30), and 32.15 days (T3; n = 36) post-concussion, wi...