Differences in serum selenoprotein P profile between C57BL/6 and BALB/c mice fed high-fat diet

• Published in: Journal of trace elements in medicine and biology Vol. 81; p. 127340
• Main Authors: Ando, Motozumi, Suzuki, Keiko, Kitamoto, Riko, Nakayama, Ayako, Watanabe, Norio, Kawahara, Masami
• Format: Journal Article
• Language: English
• Published: Germany 01.01.2024
• Subjects: Animals; Blood Glucose - metabolism; Body Weight; Diabetes Mellitus; Diet, High-Fat - adverse effects; Insulins; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Selenoprotein P; Type 2 diabetes; Insulin resistance; Hyperglycaemia; Selenoprotein P; Hepatokine; High fat diet

C57BL/6 mice generally show hyperglycaemia and insulin resistance when fed a high-fat diet (HFD) compared to those of BALB/c mice. However, whether these strains also show different expression profiles of selenoprotein P, a diabetes-related hepatokine, after HFD feeding is unclear. We investigated t...