A new bioerodible polymer insert for the controlled release of metronidazole

• Published in: Pharmaceutical research Vol. 11; no. 11; p. 1605
• Main Authors: Gates, K A, Grad, H, Birek, P, Lee, P I
• Format: Journal Article
• Language: English
• Published: United States 01.11.1994
• Subjects: Biodegradation, Environmental; Delayed-Action Preparations; Evaluation Studies as Topic; Humans; Metronidazole - administration & dosage; Pilot Projects; Polymers

This study evaluates a new class of bioerodible polymers as periodontal inserts for the controlled release of metronidazole. The system is based on association polymers formed from compatible blends of cellulose acetate phthalate (CAP) and a hydrophobic block copolymer of polyoxyethylene and polyoxy...