Targeting Oxidative Stress and Inflammatory Response for Blood-Brain Barrier Protection in Intracerebral Hemorrhage

• Published in: Antioxidants & redox signaling
• Main Authors: Chen, Shengpan, Li, Lingzhi, Peng, Chao, Bian, Chunjing, Ocak, Pinar Eser, Zhang, John H, Yang, Yong, Zhou, Dong, Chen, Guangzhong, Luo, Yumin
• Format: Journal Article
• Language: English
• Published: United States 01.07.2022
• Subjects: intracerebral hemorrhage; inflammatory response; blood–brain barrier; blood components; oxidative stress

Blood-brain barrier (BBB) disruption is a major pathological change after intracerebral hemorrhage (ICH) and is both the cause and result of oxidative stress and of the immune response post-ICH. These processes contribute to ICH-induced brain injury. After the breakdown of cerebral vessels, blood co...