Increased expression of the kynurenine pathway in mice with eosinophilic meningitis caused by Angiostrongylus cantonensis infection

• Published in: Acta tropica Vol. 256; p. 107251
• Main Authors: Tsai, Hung-Chin, Chen, Yu-Hsin, Jen, Jing-Yueh, Chang, Hui-Min
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.08.2024
• Subjects: Angiostrongylus cantonensis; Dexamethasone; Eosinophilic meningitis; Kynurenine pathway; Eosinophilic meningitis; Dexamethasone; Angiostrongylus cantonensis; Kynurenine pathway

•A. cantonensis infection inducing blood brain barrier damage, then increased the influx of tryptophan into CSF.•An imbalance of kynurenine pathway may be related to parasitic eosinophilic meningitis caused by A. cantonensis infection.•Treatment with dexamethasone significantly reduced the expressio...