Sex and Smoking Status Effects on the Early Detection of Early Lung Cancer in High-Risk Smokers Using an Electronic Nose

• Published in: IEEE transactions on biomedical engineering Vol. 62; no. 8; pp. 2044 - 2054
• Main Authors: McWilliams, Annette, Beigi, Parmida, Srinidhi, Akhila, Lam, Stephen, MacAulay, Calum E.
• Format: Journal Article
• Language: English
• Published: United States IEEE 01.08.2015
• Subjects: Accuracy; Aged; Arrays; Biomarkers - analysis; Biomedical measurement; Breath analysis; Breath Tests - methods; Cancer; Early Detection of Cancer; Electronic Nose; Female; Humans; lung cancer; Lung Neoplasms - diagnosis; Lung Neoplasms - metabolism; Lungs; Male; Middle Aged; pattern recognition; Pattern Recognition, Automated; Predictive models; Reproducibility of Results; sensor array; Smoking - metabolism; Training; Volatile Organic Compounds; Volatile Organic Compounds - analysis; lung cancer; electronic nose (e-nose); volatile organic compounds (VOCs); Breath analysis; sensor array; pattern recognition

Objective: Volatile organic compounds (VOCs) in exhaled breath as measured by electronic nose (e-nose) have utility as biomarkers to detect subjects at risk of having lung cancer in a screening setting. We hypothesize that breath analysis using an e-nose chemo-resistive sensor array could be used as...