Brain Perfusion Bridges Virtual-Reality Spatial Behavior to TPH2 Genotype for Head Acceleration Events

• Published in: Journal of neurotrauma Vol. 38; no. 10; p. 1368
• Main Authors: Chen, Yufen, Herrold, Amy A, Walter, Alexa E, Reilly, James L, Seidenberg, Peter H, Nauman, Eric A, Talavage, Thomas, Vandenbergh, David J, Slobounov, Semyon M, Breiter, Hans C
• Format: Journal Article
• Language: English
• Published: United States 15.05.2021
• Subjects: Acceleration; Athletic Injuries - complications; Athletic Injuries - genetics; Athletic Injuries - physiopathology; Brain - blood supply; Brain - physiopathology; Brain Injuries - genetics; Cerebrovascular Circulation - physiology; Football - injuries; Genotype; Humans; Magnetic Resonance Imaging; Male; Neuroimaging; Reaction Time - genetics; Spatial Behavior - physiology; Tryptophan Hydroxylase - genetics; Virtual Reality; Young Adult; neurovascular function; cerebral blood flow; virtual reality; imaging genetics; motor performance; head acceleration events

Neuroimaging demonstrates that athletes of collision sports can suffer significant changes to their brain in the absence of concussion, attributable to head acceleration event (HAE) exposure. In a sample of 24 male Division I collegiate football players, we examine the relationships between tryptoph...