Elevated levels of D-dimers increase the risk of ischaemic and haemorrhagic stroke. Findings from the EPICOR Study

• Published in: Thrombosis and haemostasis Vol. 112; no. 5; p. 941
• Main Authors: Di Castelnuovo, Augusto, Agnoli, Claudia, de Curtis, Amalia, Giurdanella, Maria Concetta, Sieri, Sabina, Mattiello, Amalia, Matullo, Giuseppe, Panico, Salvatore, Sacerdote, Carlotta, Tumino, Rosario, Vineis, Paolo, de Gaetano, Giovanni, Donati, Maria Benedetta, Iacoviello, Licia
• Format: Journal Article
• Language: English
• Published: Germany 01.11.2014
• Subjects: Adult; Aged; Biomarkers; Brain Ischemia - blood; Brain Ischemia - epidemiology; C-Reactive Protein - analysis; Case-Control Studies; Cerebral Hemorrhage - blood; Cerebral Hemorrhage - epidemiology; Comorbidity; Confounding Factors (Epidemiology); Female; Fibrin Fibrinogen Degradation Products - analysis; Follow-Up Studies; Humans; Hypertension - blood; Hypertension - epidemiology; Inflammation - blood; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Risk Assessment; Triglycerides - blood; risk factors; cerebrovascular disease; Stroke / prevention; epidemiological studies; coagulation factors

Elevated D-dimer levels are reportedly associated with coronary artery disease. It was the study objective to investigate the association of baseline D-dimer levels with strokes that occurred in the European Prospective Investigation into Cancer and Nutrition-Italy cohort. Using a nested case-cohort...