Gut metabolomic profiles in paediatric ulcerative colitis patients prior to and after receiving faecal microbiota transplants

• Published in: Gut microbiome (Cambridge, England) Vol. 4; pp. 1 - 33
• Main Authors: Khalessi Hosseini, Parastou S., Wang, Beibei, Luan, Yihui, Sun, Fengzhu, Michail, Sonia
• Format: Journal Article
• Language: English
• Published: England Cambridge University Press 2023
• Subjects: Age; Chemotherapy; COVID-19; Dysbacteriosis; Ethnicity; Feces; Gender; Hispanic people; Inflammatory bowel disease; Intestinal microflora; Metabolites; Metabolomics; Microbiota; Pandemics; Patients; Pediatrics; Phenotypes; Phenotypic variations; Probiotics; Statistical analysis; Steroids; Ulcerative colitis; Variables; Veganism; ulcerative colitis; fecal microbiota transplant; metabolomics; inflammatory bowel disease

Ulcerative colitis (UC) is an immune-mediated inflammation of the colonic mucosa. Gut microbiota dysbiosis may play a significant role in disease pathogenesis by causing shifts in metabolomic profiles within the gut. To identify differences and trends in the metabolomic profile of paediatric UC pati...