The effect of MDMA on anterior pituitary hormones: a secondary analysis of a randomized placebo-controlled trial

• Published in: Endocrine Connections Vol. 14; no. 6
• Main Authors: Atila, Cihan, Camerin, Sara-Jessica, Liechti, Matthias E, Christ-Crain, Mirjam
• Format: Journal Article
• Language: English
• Published: England Bioscientifica Ltd 01.06.2025; Bioscientifica
• Subjects: acth; adrenocorticotropic hormone; avp; copeptin; cortisol; diagnostic; ecstasy; estradiol; growth hormone; hypopituitarism; luteinizing hormone; oxytocin; posterior pituitary; prolactin; provocation; stimulation; testosterone; thyroid-stimulating hormone; thyroxine; tsh; vasopressin; copeptin; thyroxine; oxytocin; prolactin; testosterone; ecstasy; vasopressin; ACTH; TSH; hypopituitarism; luteinizing hormone; adrenocorticotropic hormone; thyroid-stimulating hormone; cortisol; provocation; posterior pituitary; AVP; diagnostic; growth hormone; LH; estradiol; stimulation
• ISSN: 2049-3614; 2049-3614
• DOI: 10.1530/EC-25-0254

3,4-Methylenedioxymethamphetamine (MDMA), a psychoactive substance, has been proposed as a novel provocation test for oxytocin deficiency. Limited evidence suggests that MDMA may also stimulate the anterior pituitary. Therefore, this analysis aimed to investigate the acute effect of MDMA on the ante...