A new method providing complementary explanation of the blood‐enriching function and mechanism of unprocessed Angelica sinensis and its four kinds of processed products based on tissue‐integrated metabolomics and confirmatory analysis

• Published in: Biomedical chromatography Vol. 36; no. 2; pp. e5252 - n/a
• Main Authors: Ji, Peng, Li, Chen‐chen, Wei, Yan‐ming, Hua, Yong‐li, Yao, Wan‐ling, Wu, Fan‐lin, Zhang, Xiao‐song, Yuan, Zi‐wen, Zhao, Nian‐shou, Zhang, Ya‐hui, Wen, Yan‐qiao
• Format: Journal Article
• Language: English
• Published: England 01.02.2022
• Subjects: Amino Acids - metabolism; Angelica sinensis (AS); Angelica sinensis - chemistry; Animals; blood deficiency syndrome (BDS); Drugs, Chinese Herbal - pharmacology; Gas Chromatography-Mass Spectrometry; Linoleic Acid - metabolism; liver; Liver - drug effects; Liver - metabolism; Male; Medicine, Chinese Traditional; Metabolome - drug effects; metabolomics; Metabolomics - methods; Mice; process; spleen; Spleen - drug effects; Spleen - metabolism; Angelica sinensis (AS); process; blood deficiency syndrome (BDS); liver; metabolomics; spleen

Angelica sinensis (AS) is a common Traditional Chinese Medicine used for tonifying blood in China. Unprocessed AS and its four kinds of processed products (ASs) are used to treat blood deficiency syndrome in the country. The different blood‐tonifying mechanisms of ASs remain unclear. In this work, a...