The expression of cell surface MHC class I heavy and light chain molecules in pre-malignant and malignant lesions of the oral mucosa

• Published in: Histopathology Vol. 11; no. 1; p. 81
• Main Authors: Prime, S S, Pitigala-Arachchi, A, Crane, I J, Rosser, T J, Scully, C
• Format: Journal Article
• Language: English
• Published: England 01.01.1987
• Subjects: beta 2-Microglobulin - analysis; Carcinoma, Squamous Cell - immunology; Carcinoma, Squamous Cell - pathology; HLA Antigens - analysis; HLA-A Antigens; HLA-B Antigens; HLA-C Antigens; Humans; Immunologic Techniques; Leukoplakia, Oral - immunology; Leukoplakia, Oral - pathology; Major Histocompatibility Complex; Mouth Mucosa - immunology; Mouth Mucosa - pathology; Mouth Neoplasms - immunology; Mouth Neoplasms - pathology; Precancerous Conditions - immunology; Precancerous Conditions - pathology

Major histocompatibility complex (MHC) class I antigenic expression was examined on epithelial cell surfaces in normal oral mucosa, non-specific oral keratoses, dysplastic epithelium adjacent to carcinomas and in invasive tumour islands of squamous cell carcinomas, using antibodies to HLA-A,B,C shar...