JA-Regulated AaGSW1–AaYABBY5/AaWRKY9 Complex Regulates Artemisinin Biosynthesis in Artemisia annua

• Published in: Plant and cell physiology Vol. 64; no. 7; pp. 771 - 785
• Main Authors: Kayani, Sadaf-Ilyas, Yanan, Ma, Fu, Xueqing, Shen, Qian, Li, Yongpeng, Rahman, Saeed-ur, Peng, Bowen, Huang, Liu, Tang, Kexuan
• Format: Journal Article
• Language: English
• Published: UK Oxford University Press 17.07.2023
• Subjects: AaYABBY5–AaWRKY9; Transcription factors; Jasmonates; Artemisinin; AaYABBY5; Artemisia annua

Abstract Artemisinin, a sesquiterpene lactone obtained from Artemisia annua, is an essential therapeutic against malaria. YABBY family transcription factor AaYABBY5 is an activator of AaCYP71AV1 (cytochrome P450–dependent hydroxylase) and AaDBR2 (double-bond reductase 2); however, the protein–protei...