Tunable reactivity of geminal bis(silyl) enol derivatives leading to selective exo-IEDDA or Sakurai allylation with a beta,gamma-unsaturated ketoester

Two contrasting pathways in a SnCl4-catalyzed reaction of geminal bis(silyl) enol derivatives with beta,gamma-unsaturated ketoesters have been achieved by tuning the R group in the enol moiety. While the electron-donating Bn-substituted enol ether undergoes an exo-selective inverse-electron-demand D...

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Bibliographic Details
Published inChemical communications (Cambridge, England) Vol. 52; no. 66; pp. 10137 - 10140
Main Authors Gan, Zubao, Chu, Zhiwen, Hu, Jia, Su, Zhishan, Hu, Changwei, Gao, Lu, Song, Zhenlei
Format Journal Article
LanguageEnglish
Published CAMBRIDGE Royal Soc Chemistry 09.08.2016
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