The association of the triglyceride-glucose index with Alzheimer's disease and its potential mechanisms

• Published in: Journal of Alzheimer's disease Vol. 102; no. 1; p. 77
• Main Authors: Zhang, Zihao, Sheng, Zehu, Liu, Jiayao, Zhang, Dandan, Wang, Hao, Wang, Lanyang, Zhu, Yangke, Ma, Lingzhi, Tan, Lan
• Format: Journal Article
• Language: English
• Published: United States 01.11.2024
• Subjects: Aged; Alzheimer Disease - blood; Alzheimer Disease - cerebrospinal fluid; Alzheimer Disease - diagnosis; Amyloid beta-Peptides - blood; Amyloid beta-Peptides - cerebrospinal fluid; Biomarkers - blood; Biomarkers - cerebrospinal fluid; Blood Glucose; Cognition - physiology; Female; Glucose - cerebrospinal fluid; Glucose - metabolism; Humans; Male; Middle Aged; Peptide Fragments - blood; Peptide Fragments - cerebrospinal fluid; tau Proteins - blood; tau Proteins - cerebrospinal fluid; Triglycerides - blood; Triglycerides - cerebrospinal fluid; alzheimer's disease; cognition; insulin resistance; triglyceride-glucose index

The correlation between Alzheimer's disease (AD) and the glucose-triglyceride (TyG) index remains undetermined. This study aimed to investigate the relationship between the TyG index and AD, as well as the relationship between the TyG index and cerebrospinal fluid (CSF) AD biomarkers and cognit...