Human Helios, an Ikaros-related zinc finger DNA binding protein: cDNA cloning and tissue expression pattern

• Published in: Immunogenetics (New York) Vol. 50; no. 1-2; pp. 106 - 108
• Main Authors: Hosokawa, Y, Maeda, Y, Seto, M
• Format: Journal Article
• Language: English
• Published: United States 01.10.1999
• Subjects: Aiolos protein; Amino Acid Sequence; Cloning, Molecular; DNA, Complementary - genetics; DNA-Binding Proteins - genetics; Helios protein; Humans; Ikaros gene; Ikaros Transcription Factor; Molecular Sequence Data; Sequence Homology, Amino Acid; Tissue Distribution; Transcription Factors - genetics; zinc finger proteins; Zinc Fingers

The molecular mechanisms that control commitment to and progression along the various hematopoietic lineages remain to be elucidated. In many development systems, transcriptional factors act as the principal control genes and are the executors of differentiation programs. The Ikaros gene encodes a f...