Decrease in Prevalence of Cleft lip, Alveolus and Palate After Nationwide Introduction of the Second-Trimester Anomaly Scan in the Netherlands

• Published in: The Cleft palate-craniofacial journal Vol. 61; no. 6; p. 930
• Main Authors: Smit, Johannes A, Bax, Caroline J, Vermeij-Keers, Christl, Trenning, Bert A H, de Bakker, Bernadette S, Breugem, Corstiaan C
• Format: Journal Article
• Language: English
• Published: United States 01.06.2024
• Subjects: Adult; Alveolar Process - abnormalities; Alveolar Process - diagnostic imaging; Cleft Lip - diagnostic imaging; Cleft Lip - epidemiology; Cleft Palate - diagnostic imaging; Cleft Palate - epidemiology; Female; Humans; Netherlands - epidemiology; Pregnancy; Pregnancy Trimester, Second; Prevalence; Retrospective Studies; Ultrasonography, Prenatal; Netherlands; epidemiology; registry; ethics/Health policies; folic acid; prenatal development; ultrasound

Some studies have suggested that introducing a second-trimester anomaly scan (SAS) leads to increased rates of termination of pregnancy (TOP) in fetuses with orofacial clefts (OFCs). The aim of this study was to evaluate the impact of a nationwide introduction of SAS on the prevalence of live births...