The evaluation of potential immunotoxicity induced by environmental pollutant ammonia in broilers

• Published in: Poultry science Vol. 98; no. 8; pp. 3165 - 3175
• Main Authors: An, Yang, Xing, Houjuan, Zhang, Yu, Jia, Pengcheng, Gu, Xianhong, Teng, Xiaohua
• Format: Journal Article
• Language: English
• Published: England 01.08.2019
• Subjects: Air Pollutants - toxicity; Air Pollution, Indoor - adverse effects; Ammonia - toxicity; Animal Husbandry; Animals; Chickens; Cytokines - metabolism; Heat-Shock Proteins - metabolism; Inflammation - chemically induced; Inflammation - genetics; Inflammation - pathology; Inflammation - veterinary; MicroRNAs; NF-kappa B; Poultry Diseases - chemically induced; Poultry Diseases - immunology; Poultry Diseases - pathology; RNA, Messenger; Signal Transduction; Spleen - immunology; Spleen - pathology; inflammatory damage; miRNAs; Th1/Th2 imbalance; compensatory response of HSPs; ammonnia

Ammonia (NH3) is a harmful gas with irritating odor, and higher NH3 concentration was found in intensive poultry houses. Although the toxicity of NH3 is well known, little attention has been given to the mechanism of NH3 poisoning in chicken immune organs. To investigate NH3-caused inflammatory dama...