The additional role of anti-nucleosome antibodies in the prediction of renal damage in systemic lupus erythematosus based on CSTAR (XXV)

• Published in: Lupus Vol. 33; no. 9; pp. 986 - 997
• Main Authors: Ding, Yufang, Zhou, Yangzhong, Zhao, Jiuliang, Wu, Chanyuan, Zhang, Shangzhu, Jiang, Nan, Qian, Junyan, Zhang, Li, Li, Jing, Xu, Dong, Leng, Xiaomei, Wang, Qian, Tian, Xinping, Li, Mengtao, Zeng, Xiaofeng
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.08.2024; Sage Publications Ltd
• Subjects: Adult; Anti-DNA antibodies; Antibodies; Antibodies, Antinuclear - blood; Antibodies, Antinuclear - immunology; Autoantibodies; Autoantibodies - blood; Autoantibodies - immunology; China; Female; Follow-Up Studies; Humans; Kidney - immunology; Kidney - pathology; Kidneys; Lupus; Lupus Erythematosus, Systemic - complications; Lupus Erythematosus, Systemic - immunology; Lupus nephritis; Lupus Nephritis - immunology; Male; Middle Aged; Multivariate Analysis; Nucleosomes - immunology; Patients; Prognosis; Proportional Hazards Models; Prospective Studies; Registries; Systemic lupus erythematosus; Young Adult; China; lupus nephritis; anti-dsDNA antibodies; Systemic lupus erythematosus; anti-nucleosome antibodies; autoantibodies

Objectives The predominant determinant of an unfavorable prognosis among Systemic Lupus Erythematosus (SLE) patients resides in the irreversible organ damage. This prospective cohort study aimed to identify the additional value of anti-nucleosome antibodies on organ damage accumulation in SLE patien...