Awake reactivation of cortical memory traces predicts subsequent memory retrieval

• Published in: Progress in neurobiology Vol. 250; p. 102778
• Main Authors: Duan, Wei, Lu, Pingping, Xu, Zhansheng, Wang, Jing, Lu, Yue, Wang, Mengyang, Paller, Ken A., Axmacher, Nikolai, Wang, Liang
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.07.2025
• Subjects: Adult; Awake reactivation; Cerebral Cortex - physiology; Cortical memory trace; Drug Resistant Epilepsy - physiopathology; Electrocorticography; Female; Hippocampal-cortical dialogue; Hippocampus - physiology; Humans; Male; Memory consolidation; Memory Consolidation - physiology; Mental Recall - physiology; Ripple; Wakefulness - physiology; Young Adult; Memory consolidation; Cortical memory trace; Awake reactivation; Ripple; Hippocampal-cortical dialogue

Brief periods of rest after learning facilitate consolidation of new memories. Memory reactivation and hippocampal-cortical dialogue have been proposed as candidate mechanisms supporting consolidation. However, the study of these mechanisms has mostly concerned sleep-based consolidation. Whether and...