Controllable protein design with language models

• Published in: Nature machine intelligence Vol. 4; no. 6; pp. 521 - 532
• Main Authors: Ferruz, Noelia, Höcker, Birte
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.06.2022; Nature Publishing Group
• Subjects: 631/114/1305; 639/705/1042; Algorithms; Amino acids; Artificial intelligence; Controllability; Custom design; Energy; Engineering; Language; Machine learning; Natural language processing; Peptides; Proteins; Review Article; Transformers

The twenty-first century is presenting humankind with unprecedented environmental and medical challenges. The ability to design novel proteins tailored for specific purposes would potentially transform our ability to respond to these issues in a timely manner. Recent advances in the field of artific...