Topical treatment of herpes simplex virus infection with enzymatically created siRNA swarm

• Published in: Antiviral therapy Vol. 22; no. 7; pp. 631 - 637
• Main Authors: Paavilainen, Henrik, Lehtinen, Jenni, Romanovskaya, Alesia, Nygårdas, Michaela, Bamford, Dennis H, Poranen, Minna M, Hukkanen, Veijo
• Format: Journal Article
• Language: English
• Published: England 01.01.2017

Herpes simplex virus (HSV) is a common human pathogen. Despite current antivirals, it causes a significant medical burden. Drug resistant strains exist and they are especially prevalent in immunocompromised patients and in HSV eye infections. New treatment modalities are needed. BALB/c mice were cor...