Gender specific association of ABCA1 gene R219K variant in coronary disease risk through interactions with serum triglyceride elevation in Turkish adults

• Published in: Anadolu kardiyoloji dergisi : AKD Vol. 14; no. 1; p. 18
• Main Authors: Coban, Neslihan, Onat, Altan, Komurcu Bayrak, Evrim, Gulec, Cagri, Can, Gunay, Erginel Unaltuna, Nihan
• Format: Journal Article
• Language: English
• Published: Turkey Kare Publishing 01.02.2014
• Subjects: Adult; ATP Binding Cassette Transporter 1 - genetics; Cholesterol - blood; Cholesterol, HDL - blood; Cholesterol, LDL - blood; Coronary Artery Disease - blood; Coronary Artery Disease - genetics; European Continental Ancestry Group; Female; Gender Identity; Genetic Predisposition to Disease; Humans; Logistic Models; Male; Polymorphism, Restriction Fragment Length; Risk Factors; Sex Factors; Triglycerides - blood; Turkey; Turkey

ATP binding cassette transporter A1 (ABCA1) controls the reverse cholesterol transport. Some ABCA1 variants are correlated with serum high-density lipoprotein cholesterol (HDL-C) and other lipid concentrations. We aimed to explore the relationship of ABCA1 gene with both the lipid profile and corona...