Histological Stains in the Past, Present, and Future
Certain contemporary histology stains and methods are not the same as those used in the past. This progression has delved into the requirement for more precise, less complex, and efficient staining procedures. The objective of this study is to assess historical and contemporary stains and procedures...
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| Published in | Curēus (Palo Alto, CA) Vol. 13; no. 10; p. e18486 |
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| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
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Palo Alto
Cureus Inc
04.10.2021
Cureus |
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| Online Access | Get full text |
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| Abstract | Certain contemporary histology stains and methods are not the same as those used in the past. This progression has delved into the requirement for more precise, less complex, and efficient staining procedures. The objective of this study is to assess historical and contemporary stains and procedures, as well as the challenges surrounding their improvement. Carmine, hematoxylin, silver nitrate, Giemsa, trichome stain, Gram stain, and mauveine were among the first histological stains discovered in nature. Aside from their utility in the study of tissues at the time, they also laid the groundwork for the development of commercial dyes that are still in use today. Hematoxylin and eosin, Ziehl-Nielsen (ZN) stain, periodic acid-Schiff stain, and Grocott-Gomori methenamine silver stain are some of the most recently developed histological stains. The future of histological stains and processes appears to be influenced by technological advancements and the demand for cost-effective diagnostic approaches in the healthcare system. Thus, currently used histological stains appear to be economical, quick, and reliable tools for interpreting, archiving, and delivering essential diagnoses that could not be achieved by any other means. |
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| AbstractList | Certain contemporary histology stains and methods are not the same as those used in the past. This progression has delved into the requirement for more precise, less complex, and efficient staining procedures. The objective of this study is to assess historical and contemporary stains and procedures, as well as the challenges surrounding their improvement. Carmine, hematoxylin, silver nitrate, Giemsa, trichome stain, Gram stain, and mauveine were among the first histological stains discovered in nature. Aside from their utility in the study of tissues at the time, they also laid the groundwork for the development of commercial dyes that are still in use today. Hematoxylin and eosin, Ziehl-Nielsen (ZN) stain, periodic acid-Schiff stain, and Grocott-Gomori methenamine silver stain are some of the most recently developed histological stains. The future of histological stains and processes appears to be influenced by technological advancements and the demand for cost-effective diagnostic approaches in the healthcare system. Thus, currently used histological stains appear to be economical, quick, and reliable tools for interpreting, archiving, and delivering essential diagnoses that could not be achieved by any other means. |
| Author | Ali, Sundus Nusrat, Areeba Ghauri, Sanniya Khan Javaeed, Arslaan Qamar, Shanza Mustafa, Mir Ahmad Talha |
| AuthorAffiliation | 2 Pathology, Rawalpindi Medical University, Rawalpindi, PAK 3 Pathology, Ziauddin University, Karachi, PAK 1 Pathology, Poonch Medical College, Rawalakot, PAK 4 Emergency Medicine, Shifa International Hospital, Islamabad, PAK |
| AuthorAffiliation_xml | – name: 4 Emergency Medicine, Shifa International Hospital, Islamabad, PAK – name: 3 Pathology, Ziauddin University, Karachi, PAK – name: 1 Pathology, Poonch Medical College, Rawalakot, PAK – name: 2 Pathology, Rawalpindi Medical University, Rawalpindi, PAK |
| Author_xml | – sequence: 1 givenname: Arslaan surname: Javaeed fullname: Javaeed, Arslaan – sequence: 2 givenname: Shanza surname: Qamar fullname: Qamar, Shanza – sequence: 3 givenname: Sundus surname: Ali fullname: Ali, Sundus – sequence: 4 givenname: Mir Ahmad Talha surname: Mustafa fullname: Mustafa, Mir Ahmad Talha – sequence: 5 givenname: Areeba surname: Nusrat fullname: Nusrat, Areeba – sequence: 6 givenname: Sanniya Khan surname: Ghauri fullname: Ghauri, Sanniya Khan |
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| CitedBy_id | crossref_primary_10_1016_j_heliyon_2024_e32546 crossref_primary_10_1101_lm_053922_124 crossref_primary_10_3390_microorganisms10061226 crossref_primary_10_1364_OL_514077 crossref_primary_10_5005_jp_journals_10015_2179 |
| Cites_doi | 10.1038/labinvest.2012.109 10.7243/2055-091X-1-5 10.1002/ase.211 10.21037/tlcr.2017.07.06 10.3389/fmicb.2021.588035 10.1177/0300985810380399 10.1126/science.77.1990.194 10.1136/jcp.52.6.461 10.1016/j.jip.2012.04.013 10.1080/10520290701704188 10.1136/jclinpath-2014-202705 10.1179/his.2009.32.1.9 10.4081/ejh.2010.e39 10.1002/9780471729259.mca03cs15 10.1109/CVPR.2014.394 10.4103/JOC.JOC_84_16 10.1007/978-1-0716-1080-0_65 10.4103/0973-1482.174548 10.1080/10520295.2017.1315456 10.1177/0300985813511132 10.1182/blood.V10.2.160.160 10.1002/sca.1998.4950200704 10.5539/gjhs.v8n3p72 10.1111/cup.12498 10.1309/LMXB668WDCBIAWJL 10.1002/9780471729259.mca03cs00 10.1046/j.1472-765x.2002.01047.x 10.4172/2329-6577.1000122 10.1007/s00264-014-2284-3 10.1002/prca.200780106 10.1007/s10278-014-9766-0 10.2174/187221512799303190 10.1080/00033790.2015.1122837 10.1055/s-0032-1333468 10.1007/s10143-006-0032-x 10.1097/DCR.0000000000000567 |
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| Copyright | Copyright © 2021, Javaeed et al. This work is published under https://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. Copyright © 2021, Javaeed et al. 2021 Javaeed et al. |
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| SubjectTerms | Alcohol Bacteria Dyes Hematology Histology Histopathology Microscopes Microscopy Pathology Stains & staining |
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| Title | Histological Stains in the Past, Present, and Future |
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