Left ventricular volume determination from single-photon emission computed tomography

• Published in: American journal of roentgenology (1976) Vol. 144; no. 2; pp. 295 - 298
• Main Authors: Bunker, , SR, Hartshorne, MF, Schmidt, WP, Cawthon, MA, Karl, RD, Jr, Bauman, JM, Howard, WH, 3rd, Rubal, BJ
• Format: Journal Article
• Language: English
• Published: United States Am Roentgen Ray Soc 01.02.1985
• Subjects: Adult; Aged; Cardiac Output; Cineangiography; Female; Heart - diagnostic imaging; Humans; Male; Middle Aged; Models, Structural; Sodium Pertechnetate Tc 99m; Stroke Volume; Tomography, Emission-Computed
• DOI: 10.2214/ajr.144.2.295
• ISSN: 0361-803X

To compare the accuracy of single-photon emission computed tomography (SPECT) with that of contrast cineangiography in measuring left ventricular end-diastolic volume, 25 consecutive patients undergoing catheterization for coronary artery or valvular heart disease were first evaluated scintigraphically. A simple, count-corrected voxel counting technique was used to derive left ventricular end-diastolic volume from transaxial SPECT slices. SPECT volume values showed a high degree of correlation with those determined by angiography (r = 0.969), with a standard error of the estimate of 23 ml. SPECT offers a highly accurate and essentially noninvasive method for measuring chamber volumes that is independent of geometric assumptions about ventricular configuration and chest wall attenuation and does not require blood sample counting.