A Reagentless Aptamer Sensor Based on a Self-Powered DNA Machine for Electrochemical Detection of AFB1

• Published in: Electrocatalysis Vol. 14; no. 4; pp. 593 - 601
• Main Authors: Wei, Guobing, Fan, Qiqi, Hong, Nian, Cui, Hanfeng, Zhang, Wenxing, Rustam, Mijit, Alim, Alxir, Jiang, Tao, Dong, Huanhuan, Fan, Hao
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.07.2023; Springer Nature B.V
• Subjects: Aflatoxins; Catalysis; Chemistry; Chemistry and Materials Science; Electrochemical analysis; Electrochemistry; Energy Systems; Monitoring; Physical Chemistry; Real time; Sensors; Substrates; Zirconium; Bisferrocene; AFB1; MOF; Real-time; DNA walker

Here, we developed a novel reagentless aptamer sensor for the detection of aflatoxin B1 (AFB1) that uses a DNA walker strategy and bisferrocene to enhance the signal. First, the special binding of AFB1 and AFB1 aptamer activates the DNAzyme strand. Then, with the aid of Mn 2+ , the DNAzyme strand se...