Dopamine Modulates Effective Connectivity in Frontal Cortex

• Published in: Journal of cognitive neuroscience Vol. 36; no. 1; pp. 155 - 166
• Main Authors: Vogelsang, David A., Furman, Daniella J., Nee, Derek E., Pappas, Ioannis, White, Robert L., Kayser, Andrew S., D'Esposito, Mark
• Format: Journal Article
• Language: English
• Published: United States MIT Press Journals, The 01.01.2024
• Subjects: Blindness; Bromocriptine; Catechol; Catechol O-Methyltransferase; Cognitive ability; Cortex (frontal); Dopamine; Dopamine Agonists - pharmacology; Dopamine D2 receptors; Frontal gyrus; Frontal Lobe - physiology; Functional magnetic resonance imaging; Hemispheric laterality; Humans; Magnetic Resonance Imaging; Methyltransferase; Neural networks; Prefrontal Cortex - physiology; Tolcapone

There is increasing evidence that the left lateral frontal cortex is hierarchically organized such that higher-order regions have an asymmetric top–down influence over lower order regions. However, questions remain about the underlying neuroarchitecture of this hierarchical control organization. Wit...