Diagnosing Pulmonary Tuberculosis in the Elderly

Purpose of Review Pulmonary tuberculosis (TB) remains a diagnostic challenge, particularly in low endemic settings with ageing populations. The impact has both individual and infection control implications. Recent Findings Over the past 20 years, progress has been made in trying to improve TB diagno...

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Published inCurrent geriatrics reports Vol. 9; no. 2; pp. 30 - 39
Main Authors Symes, Michael J., Probyn, Ben, Daneshvar, Cyrus, Telisinghe, Lilanganee
Format Journal Article
LanguageEnglish
Published New York Springer US 01.06.2020
Springer Nature B.V
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Abstract Purpose of Review Pulmonary tuberculosis (TB) remains a diagnostic challenge, particularly in low endemic settings with ageing populations. The impact has both individual and infection control implications. Recent Findings Over the past 20 years, progress has been made in trying to improve TB diagnostics. International recommendations for investigation however still rely heavily on the index of suspicion, imaging and ultimately culturing Mycobacterium tuberculosis which remains the gold standard for diagnosing TB disease. Recent advances include molecular diagnostics with the ability to rapidly identify TB disease and drug resistance and whole-genome sequencing. Summary In this review, we explore the validity of TB diagnostics in the elderly to assist the practicing clinician in the diagnostic workup in this population.
AbstractList Purpose of Review Pulmonary tuberculosis (TB) remains a diagnostic challenge, particularly in low endemic settings with ageing populations. The impact has both individual and infection control implications. Recent Findings Over the past 20 years, progress has been made in trying to improve TB diagnostics. International recommendations for investigation however still rely heavily on the index of suspicion, imaging and ultimately culturing Mycobacterium tuberculosis which remains the gold standard for diagnosing TB disease. Recent advances include molecular diagnostics with the ability to rapidly identify TB disease and drug resistance and whole-genome sequencing. Summary In this review, we explore the validity of TB diagnostics in the elderly to assist the practicing clinician in the diagnostic workup in this population.
Purpose of ReviewPulmonary tuberculosis (TB) remains a diagnostic challenge, particularly in low endemic settings with ageing populations. The impact has both individual and infection control implications.Recent FindingsOver the past 20 years, progress has been made in trying to improve TB diagnostics. International recommendations for investigation however still rely heavily on the index of suspicion, imaging and ultimately culturing Mycobacterium tuberculosis which remains the gold standard for diagnosing TB disease. Recent advances include molecular diagnostics with the ability to rapidly identify TB disease and drug resistance and whole-genome sequencing.SummaryIn this review, we explore the validity of TB diagnostics in the elderly to assist the practicing clinician in the diagnostic workup in this population.
Author Telisinghe, Lilanganee
Daneshvar, Cyrus
Probyn, Ben
Symes, Michael J.
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  givenname: Lilanganee
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  organization: Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine
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Issue 2
Keywords Diagnostics
Sputum microscopy
Whole-genome sequencing
Elderly
Imaging
Language English
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Snippet Purpose of Review Pulmonary tuberculosis (TB) remains a diagnostic challenge, particularly in low endemic settings with ageing populations. The impact has both...
Purpose of ReviewPulmonary tuberculosis (TB) remains a diagnostic challenge, particularly in low endemic settings with ageing populations. The impact has both...
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SubjectTerms Age groups
Bronchoscopy
Comorbidity
Fever
Geriatrics/Gerontology
HIV
Human immunodeficiency virus
Industrialized nations
Infections
Medicine
Medicine & Public Health
Microscopy
Neurology
Older people
Pain Medicine
Pathogens
Patients
Psychopharmacology
Pulmonology and Respiratory Care (D Breen
Rheumatology
Section Editor
Subject heading schemes
Substance abuse treatment
Topical Collection on Pulmonology and Respiratory Care
Tuberculosis
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