Diagnosing Pulmonary Tuberculosis in the Elderly
Purpose of Review Pulmonary tuberculosis (TB) remains a diagnostic challenge, particularly in low endemic settings with ageing populations. The impact has both individual and infection control implications. Recent Findings Over the past 20 years, progress has been made in trying to improve TB diagno...
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Published in | Current geriatrics reports Vol. 9; no. 2; pp. 30 - 39 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
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New York
Springer US
01.06.2020
Springer Nature B.V |
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Abstract | Purpose of Review
Pulmonary tuberculosis (TB) remains a diagnostic challenge, particularly in low endemic settings with ageing populations. The impact has both individual and infection control implications.
Recent Findings
Over the past 20 years, progress has been made in trying to improve TB diagnostics. International recommendations for investigation however still rely heavily on the index of suspicion, imaging and ultimately culturing
Mycobacterium tuberculosis
which remains the gold standard for diagnosing TB disease. Recent advances include molecular diagnostics with the ability to rapidly identify TB disease and drug resistance and whole-genome sequencing.
Summary
In this review, we explore the validity of TB diagnostics in the elderly to assist the practicing clinician in the diagnostic workup in this population. |
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AbstractList | Purpose of Review
Pulmonary tuberculosis (TB) remains a diagnostic challenge, particularly in low endemic settings with ageing populations. The impact has both individual and infection control implications.
Recent Findings
Over the past 20 years, progress has been made in trying to improve TB diagnostics. International recommendations for investigation however still rely heavily on the index of suspicion, imaging and ultimately culturing
Mycobacterium tuberculosis
which remains the gold standard for diagnosing TB disease. Recent advances include molecular diagnostics with the ability to rapidly identify TB disease and drug resistance and whole-genome sequencing.
Summary
In this review, we explore the validity of TB diagnostics in the elderly to assist the practicing clinician in the diagnostic workup in this population. Purpose of ReviewPulmonary tuberculosis (TB) remains a diagnostic challenge, particularly in low endemic settings with ageing populations. The impact has both individual and infection control implications.Recent FindingsOver the past 20 years, progress has been made in trying to improve TB diagnostics. International recommendations for investigation however still rely heavily on the index of suspicion, imaging and ultimately culturing Mycobacterium tuberculosis which remains the gold standard for diagnosing TB disease. Recent advances include molecular diagnostics with the ability to rapidly identify TB disease and drug resistance and whole-genome sequencing.SummaryIn this review, we explore the validity of TB diagnostics in the elderly to assist the practicing clinician in the diagnostic workup in this population. |
Author | Telisinghe, Lilanganee Daneshvar, Cyrus Probyn, Ben Symes, Michael J. |
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Cites_doi | 10.5588/ijtld.11.0778 10.1007/s00259-007-0585-0 10.1002/14651858.CD009593.pub4 10.1016/j.tube.2014.10.006 10.1016/j.athoracsur.2005.11.010 10.1111/j.1532-5415.1987.tb01396.x 10.1001/jama.2014.11488 10.1378/chest.116.4.961 10.1183/23120541.00228-2018 10.1016/j.ccm.2007.07.004 10.1111/j.1532-5415.1993.tb06735.x 10.1093/cid/ciw778 10.1007/s00330-014-3279-6 10.1053/j.semnuclmed.2017.10.005 10.1097/MD.0000000000016921 10.1111/j.1440-1843.2010.01784.x 10.1155/2013/828939 10.3109/00365548.2011.643820 10.1016/j.jrid.2017.11.001 10.1186/1471-2334-14-23 10.1378/chest.109.2.420 10.1093/ageing/afs028 10.1136/postgradmedj-2015-133278 10.1007/s00784-019-02864-6 10.1016/j.ejrad.2011.09.002 10.1111/jgs.13437 10.1136/thx.51.2.132 10.1128/CMR.00021-18 10.3346/jkms.2005.20.5.784 10.1164/ajrccm.152.5.7582296 10.1136/thx.48.12.1257 10.1097/MCP.0b013e328351f9d6 10.1164/ajrccm-conference.2011.183.1_MeetingAbstracts.A1195 10.1378/chest.106.1.28 10.1186/1471-2334-13-121 10.2214/AJR.14.13483 10.1007/s15010-008-7199-8 10.1080/10428194.2018.1499904 10.1136/thorax.57.12.1010 10.1378/chest.92.2.237 10.1378/chest.08-0434 10.1183/13993003.02678-2017 10.1378/chest.07-1995 10.5588/ijtld.13.0871 10.3892/etm.2017.4737 10.1111/j.1532-5415.2011.03369.x 10.1378/chest.124.3.893 10.1111/j.1532-5415.2007.01316.x 10.1016/j.jctube.2019.100106 10.1371/journal.pone.0156917 10.1503/cmaj.091824 10.1097/00007611-199007000-00007 10.1016/j.ejrad.2011.03.028 10.1186/s40249-018-0403-x 10.1016/j.ijid.2014.12.007 |
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References | Yeh JJ, Chen SC, Chen CR, Yeh TC, Lin HK, Hong JB, et al. A high-resolution computed tomography-based scoring system to differentiate the most infectious active pulmonary tuberculosis from community-acquired pneumonia in elderly and non-elderly patients. Eur Radiol. 24(10):2372–84. BhushanBKajalNCMaskeASinghSPManifestations of tuberculosis in elderly versus young hospitalised patients in Amritsar, IndiaInt J Tuberc Lung Dis2012169121012131:STN:280:DC%2BC38jpvVGrsg%3D%3D22794086 KimYKHahnSUhYImDJLimYLChoiHKComparable characteristics of tuberculous and non-tuberculous mycobacterial cavitary lung diseasesInternational Journal of Tuberculosis & Lung Disease.20141867257291:STN:280:DC%2BC2cfgtVSlsw%3D%3D NisarMWilliamsCSAshbyDDaviesPDTuberculin testing in residential homes for the elderlyThorax.19934812125712601:STN:280:DyaK2c7jsFKmsg%3D%3D8303634464987 McWilliamsTWellsAUHarrisonACLindstromSCameronRJFoskinEInduced sputum and bronchoscopy in the diagnosis of pulmonary tuberculosisThorax.20025712101010141:STN:280:DC%2BD38nptlKluw%3D%3D124542931758793 CudahyPShenoiSVDiagnostics for pulmonary tuberculosisPostgrad Med J2016921086187193270052714854647 Cruz-Hervert LP, Garcia-Garcia L, Ferreyra-Reyes L, Bobadilla-del-Valle M, Cano-Arellano B, Canizales-Quintero S, et al. Tuberculosis in ageing: high rates, complex diagnosis and poor clinical outcomes. Age Ageing. 41(4):488–95. HoldenMTuberculin sensitivity in elderly patientsAm Rev Respir Dis197210558548551:STN:280:DyaE387msFGhug%3D%3D5020637 KimJHKimMJHamSYClinical characteristics and chest computed tomography findings of smear-positive and smear-negative pulmonary tuberculosis in hospitalized adult patientsMedicine20199834e16921314418756716700A useful contemporary study for clinicians describing the different radiographical features in smear positive and negative patients. LewinsohnDMLeonardMKLoBuePACohnDLDaleyCLDesmondEKeaneJLewinsohnDALoefflerAMMazurekGHO'BrienRJPaiMRicheldiLSalfingerMShinnickTMSterlingTRWarshauerDMWoodsGLOfficial American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention clinical practice guidelines: diagnosis of tuberculosis in adults and childrenClin Infect Dis2017642111115280529675504475 MorrisCDNellHEpidemic of pulmonary tuberculosis in geriatric homesS Afr Med J19887431171201:STN:280:DyaL1c3ptVylsg%3D%3D3261044Suid-Afrikaanse Tydskrif Vir Geneeskunde SkouraEZumlaABomanjiJImaging in tuberculosisInt J Infect Dis201532879325809762 DorkenEGrzybowskiSAllenEASignificance of the tuberculin test in the elderlyChest.19879222372401:STN:280:DyaL2s3nsFWjtw%3D%3D3111795 AbbaraACollinSMKonOMBuellKSullivanABarrettJTime to diagnosis of tuberculosis is greater in older patients: a retrospective cohort reviewERJ Open Res2019540022802018317202966826249 SoussanMBrilletPYMekinianAKhafagyANicolasPVessieresABraunerMPatterns of pulmonary tuberculosis on FDG-PET/CTEur J Radiol201281102872287621945403 FerraraGMurrayMWinthropKCentisRSotgiuGMiglioriGBMaeurerMZumlaARisk factors associated with pulmonary tuberculosis: smoking, diabetes and anti-TNFalpha drugsCurr Opin Pulm Med20121832332401:CAS:528:DC%2BC38XksFWmsbY%3D22388583 Public Health England. Tuberculosis in England: 2019 Report. PHE Publications; 2019. Konno A, Narumoto O, Matsui H, Takeda K, Hirano Y, Shinfuku K, et al. The benefit of stool mycobacterial examination to diagnose pulmonary tuberculosis for adult and elderly patients. J Clin Tuberc Other Mycobact Dis. 2019;16(100106). ChengMPAbou ChakraCNYansouniCPCnossenSShrierIMenziesDGreenawayCRisk of active tuberculosis in patients with Cancer: a systematic review and meta-analysisClin Infect Dis201764563564427986665 LinCHChenTMChangCCTsaiCHChaiWHWenJHUnilateral lower lung field opacities on chest radiography: a comparison of the clinical manifestations of tuberculosis and pneumoniaEur J Radiol2011814e426e43021555195 RozenshteinAHaoFStarcMTPearsonGDRadiographic appearance of pulmonary tuberculosis: dogma disprovedAJR Am J Roentgenol2015204597497825905930 Horne DJ, Kohli M, Zifodya JS, Schiller I, Dendukuri N, Tollefson D, et al. Xpert MTB/RIF and Xpert MTB/RIF Ultra for pulmonary tuberculosis and rifampicin resistance in adults. Cochrane Database Syst Rev. 2019;6. World Health Organisation. Global tuberculosis report 2019 https://www.who.int/tb/publications/global_report/en/2019. PandeJNSinghSPKhilnaniGCKhilnaniSTandonRKRisk factors for hepatotoxicity from antituberculosis drugs: a case-control studyThorax.19965121321361:STN:280:DyaK283ks1KhsA%3D%3D8711642473016 LeeJHHanDHSongJWChungHSDiagnostic and therapeutic problems of pulmonary tuberculosis in elderly patientsJ Korean Med Sci2005205784789162241522779275 TengCJHuonLKZhengYMYehCMTsaiCKLiuJHIncreased risk of tuberculosis in oral cancer patients in an endemic area: a nationwide population-based studyClin Oral Investig201923124223423130820823 Mehta J, Krish G, Berro E, Harvill L. Fiberoptic bronchoscopy in the diagnosis of pulmonary tuberculosis. South Med J. 83(7):753–5. Chen J, Byanju S, Zhang H, Zhu D, Liao M. CT-guided percutaneous core needle biopsy of pulmonary tuberculosis: diagnostic accuracy and complications. Radiol Infect Dis. 5(2):69–75. ChitnisASRobskyKSchecterGFWestenhouseJBarryPMTrends in tuberculosis cases among nursing home residents, California, 2000 to 2009J Am Geriatr Soc20156361098110426096384 JanssensJPClinical utility of the interferon-gamma release assay for elderly patients with active tuberculosis: a word of cautionChest.2008134247147218682477 Chan-YeungMDaiDLKCheungAHKChanFHWKamKMTamCMLeungCCTuberculin skin test reaction and body mass index in old age home residents in Hong KongJ Am Geriatr Soc200755101592159717908061 WangC-SChenH-CYangC-JWangW-YChongI-WHwangJ-JHuangMSThe impact of age on the demographic, clinical, radiographic characteristics and treatment outcomes of pulmonary tuberculosis patients in TaiwanInfection.200836433534018629436 PrattRHWinstonCAKammererJSArmstrongLRTuberculosis in older adults in the United States, 1993–2008J Am Geriatr Soc201159585185721517786 ChangCHChenYFWuVCShuCCLeeCHWangJYAcute kidney injury due to anti-tuberculosis drugs: a five-year experience in an aging populationBMC Infect Dis20141423244109583898246 RiederHLLauritsenJMNaranbatNKatambaALaticevschiDMabaeraBQuantitative differences in sputum smear microscopy results for acid-fast bacilli by age and sex in four countriesInt J Tuberc Lung Dis20091311139313981:STN:280:DC%2BD1MjitVSrtw%3D%3D19861012 NarasimhanPWoodJMacintyreCRMathaiDRisk factors for tuberculosisPulm Med20132013828939234767643583136 SchaafHSCollinsABekkerADaviesPDOTuberculosis at extremes of ageRespirology.201015574776320546192 Korzeniewska-KoselaMKryslJMüllerNBlackWAllenEFitzGeraldJMTuberculosis in young adults and the elderly: a prospective comparison studyCHEST.1994106128321:STN:280:DyaK2c3ptFeqtg%3D%3D8020286 CohenRMuzaffarSCapellanJAzarHChinikamwalaMThe validity of classic symptoms and chest radiographic configuration in predicting pulmonary tuberculosisChest.199610924204231:STN:280:DyaK287oslKltg%3D%3D8620716 PatelYRMehtaJBHarvillLGateleyKFlexible bronchoscopy as a diagnostic tool in the evaluation of pulmonary tuberculosis in an elderly populationJ Am Geriatr Soc19934166296321:STN:280:DyaK3s3otVersw%3D%3D8505460 GanzelCSilvermanBChemtobDBen ShohamAWiener-WellYThe risk of tuberculosis in cancer patients is greatest in lymphoma and myelodysplastic syndrome/myeloproliferative neoplasm: a large population-based cohort studyLeuk Lymphoma20196037207251:CAS:528:DC%2BC1cXhslWhu7jM30188229 Cruz-HervertLPGarcia-GarciaLFerreyra-ReyesLBobadilla-del-ValleMCano-ArellanoBCanizales-QuinteroSTuberculosis in ageing: high rates, complex diagnosis and poor clinical outcomesAge Ageing2012414488495224311553377131This prospective study is specific to the aging population and describes the clinical spectrum and compares to younger age groups. KwonYSChiSYOhIJKimKSKimYILimSCClinical characteristics and treatment outcomes of tuberculosis in the elderly: a case control studyBMC Infect Dis2013131121235104033599150 LangSSunJWangXXiaoYWangJZhangMAoTWangJAsymptomatic pulmonary tuberculosis mimicking lung cancer on imaging: a retrospective studyExp Ther Med201714321802188289621395609136 DeppenSABlumeJDKensingerCDMorganAMAldrichMCMassionPPWalkerRCMcPheetersMPutnam JB JrGroganELAccuracy of FDG-PET to diagnose lung cancer in areas with infectious lung disease: a meta-analysisJAMA.201431212122712361:CAS:528:DC%2BC2cXhvVCjt7fP252475194315183 KobashiYMouriKYagiSObaseYMiyashitaNOkimotoNMatsushimaTKageokaTOkaMClinical utility of the QuantiFERON TB-2G test for elderly patients with active tuberculosisChest.200813351196120218263689 LiuXHouXFGaoLDengGFZhangMXDengQYIndicators for prediction of Mycobacterium tuberculosis positivity detected with bronchoalveolar lavage fluidInfect Dis Poverty20187122295802765868051This study although retrospective reports on > 1500 smear-negative/non-sputum producers with suspected TB, reporting on the diagnostic yield of bronchoalveolar lavages. KatzPRReichmanWDubeDFeatherJClinical features of pulmonary tuberculosis in young and old veteransJ Am Geriatr Soc19873565125151:STN:280:DyaL2s7psF2ksw%3D%3D3571803 NardellEATuberculosis in homeless, residential care facilities, prisons, nursing homes, and other close communitiesSemin Respir Infect1989432062151:STN:280:DyaK3c%2FosVSmsw%3D%3D2688004 SchlugerNWTuberculosis and nontuberculous mycobacterial infections in older adultsClin Chest Med2007284773781179672932278034vi KimIJLeeJSKimSJKimYKJeongYJJunSNamHYKimJSDouble-phase 18F-FDG PET-CT for determination of pulmonary tuberculoma activityEur J Nucl Med Mol Imaging200835480881418097664 Drain PK, Bajema KL, Dowdy D, Dheda K, Naidoo K, Schumacher SG, et al. Incipient and Subclinical Tuberculosis: a Clinical Review of Early Stages and Progression of Infection. Clin Microbiol Rev. 2018;31(4). An excellent review of the spectrum of TB infection, highlighting the different stages of infection with elimination, latent TB, incipient TB, subclinical and active dise JP Janssens (319_CR67) 2008; 134 YS Kwon (319_CR26) 2013; 13 M Korzeniewska-Kosela (319_CR21) 1994; 106 P Cudahy (319_CR13) 2016; 92 CJ Teng (319_CR15) 2019; 23 M Holden (319_CR63) 1972; 105 T Hara (319_CR37) 2003; 124 MP Cheng (319_CR17) 2017; 64 319_CR27 319_CR66 319_CR65 B Bhushan (319_CR24) 2012; 16 P Chinnakali (319_CR46) 2014; 2014 M Malekmohammad (319_CR54) 2012; 44 X Liu (319_CR56) 2018; 7 Y Kobashi (319_CR64) 2008; 133 S Lang (319_CR38) 2017; 14 M Chan-Yeung (319_CR62) 2007; 55 OD Beresford (319_CR59) 1958; 77 YK Kim (319_CR34) 2014; 18 JM Van Dijk (319_CR22) 1993; 42 E Dorken (319_CR60) 1987; 92 G Ferrara (319_CR14) 2012; 18 C Anderson (319_CR52) 1995; 152 JD Hosford (319_CR10) 2015; 95 R Cohen (319_CR29) 1996; 109 JH Lee (319_CR30) 2005; 20 IJ Kim (319_CR39) 2008; 35 319_CR1 319_CR2 T McWilliams (319_CR51) 2002; 57 LP Cruz-Hervert (319_CR25) 2012; 41 AO Ankrah (319_CR36) 2018; 48 E Skoura (319_CR41) 2015; 32 P Narasimhan (319_CR19) 2013; 2013 C Perez-Guzman (319_CR23) 1999; 116 C-S Wang (319_CR44) 2008; 36 AS Chitnis (319_CR48) 2015; 63 EA Nardell (319_CR18) 1989; 4 HL Rieder (319_CR47) 2009; 13 BM Smith (319_CR12) 2011; 183 HS Schaaf (319_CR42) 2010; 15 A Abbara (319_CR3) 2019; 5 319_CR5 C Ganzel (319_CR16) 2019; 60 319_CR4 CD Morris (319_CR31) 1988; 74 319_CR7 JH Kim (319_CR33) 2019; 98 PR Katz (319_CR20) 1987; 35 CH Lin (319_CR32) 2011; 81 319_CR45 M Soussan (319_CR40) 2012; 81 NW Schluger (319_CR8) 2007; 28 319_CR50 M Nisar (319_CR61) 1993; 48 SA Deppen (319_CR35) 2014; 312 DM Lewinsohn (319_CR6) 2017; 64 A Rozenshtein (319_CR28) 2015; 204 RH Pratt (319_CR49) 2011; 59 JN Pande (319_CR9) 1996; 51 319_CR55 CH Chang (319_CR11) 2014; 14 YR Patel (319_CR53) 1993; 41 MA Smith (319_CR43) 2006; 81 319_CR58 319_CR57 |
References_xml | – volume: 16 start-page: 1210 issue: 9 year: 2012 ident: 319_CR24 publication-title: Int J Tuberc Lung Dis doi: 10.5588/ijtld.11.0778 contributor: fullname: B Bhushan – volume: 35 start-page: 808 issue: 4 year: 2008 ident: 319_CR39 publication-title: Eur J Nucl Med Mol Imaging doi: 10.1007/s00259-007-0585-0 contributor: fullname: IJ Kim – ident: 319_CR50 doi: 10.1002/14651858.CD009593.pub4 – volume: 64 start-page: 635 issue: 5 year: 2017 ident: 319_CR17 publication-title: Clin Infect Dis contributor: fullname: MP Cheng – volume: 95 start-page: 112 issue: 2 year: 2015 ident: 319_CR10 publication-title: Tuberculosis (Edinb) doi: 10.1016/j.tube.2014.10.006 contributor: fullname: JD Hosford – volume: 81 start-page: 1824 issue: 5 year: 2006 ident: 319_CR43 publication-title: Ann Thorac Surg doi: 10.1016/j.athoracsur.2005.11.010 contributor: fullname: MA Smith – ident: 319_CR1 – volume: 35 start-page: 512 issue: 6 year: 1987 ident: 319_CR20 publication-title: J Am Geriatr Soc doi: 10.1111/j.1532-5415.1987.tb01396.x contributor: fullname: PR Katz – volume: 312 start-page: 1227 issue: 12 year: 2014 ident: 319_CR35 publication-title: JAMA. doi: 10.1001/jama.2014.11488 contributor: fullname: SA Deppen – volume: 116 start-page: 961 issue: 4 year: 1999 ident: 319_CR23 publication-title: Chest. doi: 10.1378/chest.116.4.961 contributor: fullname: C Perez-Guzman – volume: 5 start-page: 00228 issue: 4 year: 2019 ident: 319_CR3 publication-title: ERJ Open Res doi: 10.1183/23120541.00228-2018 contributor: fullname: A Abbara – volume: 28 start-page: 773 issue: 4 year: 2007 ident: 319_CR8 publication-title: Clin Chest Med doi: 10.1016/j.ccm.2007.07.004 contributor: fullname: NW Schluger – volume: 41 start-page: 629 issue: 6 year: 1993 ident: 319_CR53 publication-title: J Am Geriatr Soc doi: 10.1111/j.1532-5415.1993.tb06735.x contributor: fullname: YR Patel – volume: 64 start-page: 111 issue: 2 year: 2017 ident: 319_CR6 publication-title: Clin Infect Dis doi: 10.1093/cid/ciw778 contributor: fullname: DM Lewinsohn – volume: 105 start-page: 854 issue: 5 year: 1972 ident: 319_CR63 publication-title: Am Rev Respir Dis contributor: fullname: M Holden – ident: 319_CR5 doi: 10.1007/s00330-014-3279-6 – volume: 48 start-page: 108 issue: 2 year: 2018 ident: 319_CR36 publication-title: Semin Nucl Med doi: 10.1053/j.semnuclmed.2017.10.005 contributor: fullname: AO Ankrah – volume: 98 start-page: e16921 issue: 34 year: 2019 ident: 319_CR33 publication-title: Medicine doi: 10.1097/MD.0000000000016921 contributor: fullname: JH Kim – volume: 15 start-page: 747 issue: 5 year: 2010 ident: 319_CR42 publication-title: Respirology. doi: 10.1111/j.1440-1843.2010.01784.x contributor: fullname: HS Schaaf – volume: 2013 start-page: 828939 year: 2013 ident: 319_CR19 publication-title: Pulm Med doi: 10.1155/2013/828939 contributor: fullname: P Narasimhan – volume: 44 start-page: 369 issue: 5 year: 2012 ident: 319_CR54 publication-title: Scand J Infect Dis doi: 10.3109/00365548.2011.643820 contributor: fullname: M Malekmohammad – ident: 319_CR2 – ident: 319_CR58 doi: 10.1016/j.jrid.2017.11.001 – volume: 14 start-page: 23 year: 2014 ident: 319_CR11 publication-title: BMC Infect Dis doi: 10.1186/1471-2334-14-23 contributor: fullname: CH Chang – volume: 109 start-page: 420 issue: 2 year: 1996 ident: 319_CR29 publication-title: Chest. doi: 10.1378/chest.109.2.420 contributor: fullname: R Cohen – volume: 41 start-page: 488 issue: 4 year: 2012 ident: 319_CR25 publication-title: Age Ageing doi: 10.1093/ageing/afs028 contributor: fullname: LP Cruz-Hervert – volume: 92 start-page: 187 issue: 1086 year: 2016 ident: 319_CR13 publication-title: Postgrad Med J doi: 10.1136/postgradmedj-2015-133278 contributor: fullname: P Cudahy – volume: 23 start-page: 4223 issue: 12 year: 2019 ident: 319_CR15 publication-title: Clin Oral Investig doi: 10.1007/s00784-019-02864-6 contributor: fullname: CJ Teng – volume: 81 start-page: 2872 issue: 10 year: 2012 ident: 319_CR40 publication-title: Eur J Radiol doi: 10.1016/j.ejrad.2011.09.002 contributor: fullname: M Soussan – volume: 63 start-page: 1098 issue: 6 year: 2015 ident: 319_CR48 publication-title: J Am Geriatr Soc doi: 10.1111/jgs.13437 contributor: fullname: AS Chitnis – volume: 51 start-page: 132 issue: 2 year: 1996 ident: 319_CR9 publication-title: Thorax. doi: 10.1136/thx.51.2.132 contributor: fullname: JN Pande – ident: 319_CR4 doi: 10.1128/CMR.00021-18 – volume: 20 start-page: 784 issue: 5 year: 2005 ident: 319_CR30 publication-title: J Korean Med Sci doi: 10.3346/jkms.2005.20.5.784 contributor: fullname: JH Lee – volume: 152 start-page: 1570 issue: 5 Pt 1 year: 1995 ident: 319_CR52 publication-title: Am J Respir Crit Care Med doi: 10.1164/ajrccm.152.5.7582296 contributor: fullname: C Anderson – volume: 13 start-page: 1393 issue: 11 year: 2009 ident: 319_CR47 publication-title: Int J Tuberc Lung Dis contributor: fullname: HL Rieder – volume: 48 start-page: 1257 issue: 12 year: 1993 ident: 319_CR61 publication-title: Thorax. doi: 10.1136/thx.48.12.1257 contributor: fullname: M Nisar – volume: 18 start-page: 233 issue: 3 year: 2012 ident: 319_CR14 publication-title: Curr Opin Pulm Med doi: 10.1097/MCP.0b013e328351f9d6 contributor: fullname: G Ferrara – ident: 319_CR66 doi: 10.1164/ajrccm-conference.2011.183.1_MeetingAbstracts.A1195 – volume: 106 start-page: 28 issue: 1 year: 1994 ident: 319_CR21 publication-title: CHEST. doi: 10.1378/chest.106.1.28 contributor: fullname: M Korzeniewska-Kosela – volume: 13 start-page: 121 issue: 1 year: 2013 ident: 319_CR26 publication-title: BMC Infect Dis doi: 10.1186/1471-2334-13-121 contributor: fullname: YS Kwon – volume: 204 start-page: 974 issue: 5 year: 2015 ident: 319_CR28 publication-title: AJR Am J Roentgenol doi: 10.2214/AJR.14.13483 contributor: fullname: A Rozenshtein – ident: 319_CR7 – volume: 42 start-page: 12 issue: 1 year: 1993 ident: 319_CR22 publication-title: Neth J Med contributor: fullname: JM Van Dijk – volume: 36 start-page: 335 issue: 4 year: 2008 ident: 319_CR44 publication-title: Infection. doi: 10.1007/s15010-008-7199-8 contributor: fullname: C-S Wang – volume: 60 start-page: 720 issue: 3 year: 2019 ident: 319_CR16 publication-title: Leuk Lymphoma doi: 10.1080/10428194.2018.1499904 contributor: fullname: C Ganzel – volume: 57 start-page: 1010 issue: 12 year: 2002 ident: 319_CR51 publication-title: Thorax. doi: 10.1136/thorax.57.12.1010 contributor: fullname: T McWilliams – volume: 2014 start-page: 5 year: 2014 ident: 319_CR46 publication-title: J Respir Med contributor: fullname: P Chinnakali – volume: 74 start-page: 117 issue: 3 year: 1988 ident: 319_CR31 publication-title: S Afr Med J contributor: fullname: CD Morris – volume: 92 start-page: 237 issue: 2 year: 1987 ident: 319_CR60 publication-title: Chest. doi: 10.1378/chest.92.2.237 contributor: fullname: E Dorken – volume: 134 start-page: 471 issue: 2 year: 2008 ident: 319_CR67 publication-title: Chest. doi: 10.1378/chest.08-0434 contributor: fullname: JP Janssens – ident: 319_CR27 doi: 10.1183/13993003.02678-2017 – volume: 133 start-page: 1196 issue: 5 year: 2008 ident: 319_CR64 publication-title: Chest. doi: 10.1378/chest.07-1995 contributor: fullname: Y Kobashi – volume: 77 start-page: 323 issue: 2 year: 1958 ident: 319_CR59 publication-title: Am Rev Tuberc contributor: fullname: OD Beresford – volume: 18 start-page: 725 issue: 6 year: 2014 ident: 319_CR34 publication-title: International Journal of Tuberculosis & Lung Disease. doi: 10.5588/ijtld.13.0871 contributor: fullname: YK Kim – volume: 14 start-page: 2180 issue: 3 year: 2017 ident: 319_CR38 publication-title: Exp Ther Med doi: 10.3892/etm.2017.4737 contributor: fullname: S Lang – volume: 59 start-page: 851 issue: 5 year: 2011 ident: 319_CR49 publication-title: J Am Geriatr Soc doi: 10.1111/j.1532-5415.2011.03369.x contributor: fullname: RH Pratt – volume: 124 start-page: 893 issue: 3 year: 2003 ident: 319_CR37 publication-title: Chest. doi: 10.1378/chest.124.3.893 contributor: fullname: T Hara – volume: 55 start-page: 1592 issue: 10 year: 2007 ident: 319_CR62 publication-title: J Am Geriatr Soc doi: 10.1111/j.1532-5415.2007.01316.x contributor: fullname: M Chan-Yeung – ident: 319_CR45 doi: 10.1093/ageing/afs028 – ident: 319_CR57 doi: 10.1016/j.jctube.2019.100106 – ident: 319_CR65 doi: 10.1371/journal.pone.0156917 – volume: 183 start-page: E173 issue: 3 year: 2011 ident: 319_CR12 publication-title: CMAJ. doi: 10.1503/cmaj.091824 contributor: fullname: BM Smith – ident: 319_CR55 doi: 10.1097/00007611-199007000-00007 – volume: 4 start-page: 206 issue: 3 year: 1989 ident: 319_CR18 publication-title: Semin Respir Infect contributor: fullname: EA Nardell – volume: 81 start-page: e426 issue: 4 year: 2011 ident: 319_CR32 publication-title: Eur J Radiol doi: 10.1016/j.ejrad.2011.03.028 contributor: fullname: CH Lin – volume: 7 start-page: 22 issue: 1 year: 2018 ident: 319_CR56 publication-title: Infect Dis Poverty doi: 10.1186/s40249-018-0403-x contributor: fullname: X Liu – volume: 32 start-page: 87 year: 2015 ident: 319_CR41 publication-title: Int J Infect Dis doi: 10.1016/j.ijid.2014.12.007 contributor: fullname: E Skoura |
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Pulmonary tuberculosis (TB) remains a diagnostic challenge, particularly in low endemic settings with ageing populations. The impact has both... Purpose of ReviewPulmonary tuberculosis (TB) remains a diagnostic challenge, particularly in low endemic settings with ageing populations. The impact has both... |
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SubjectTerms | Age groups Bronchoscopy Comorbidity Fever Geriatrics/Gerontology HIV Human immunodeficiency virus Industrialized nations Infections Medicine Medicine & Public Health Microscopy Neurology Older people Pain Medicine Pathogens Patients Psychopharmacology Pulmonology and Respiratory Care (D Breen Rheumatology Section Editor Subject heading schemes Substance abuse treatment Topical Collection on Pulmonology and Respiratory Care Tuberculosis |
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