Infections, Pandemics, and Sleep Disorders

Studies of the neurological symptoms and signs associated with the acute and late phases of infectious diseases are important in pandemic conditions. The novel coronavirus infection (COVID-19) pandemic has increased the number of patients with sleeplessness, this being an adverse prognostic factor f...

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Published inNeuroscience and behavioral physiology Vol. 52; no. 3; pp. 319 - 325
Main Authors Kolokolov, O. V., Salina, E. A., Yudina, V. V., Shuldyakov, A. A., Runnova, A. E.
Format Journal Article
LanguageEnglish
Published Cham Springer International Publishing 2022
Springer Nature B.V
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Abstract Studies of the neurological symptoms and signs associated with the acute and late phases of infectious diseases are important in pandemic conditions. The novel coronavirus infection (COVID-19) pandemic has increased the number of patients with sleeplessness, this being an adverse prognostic factor for infections. This review addresses the factors and mechanisms of sleep impairments and their relationship with inflammation and immune system dysfunction in infectious diseases. In particular, impairments to the functioning of the melatoninergic system are discussed as the cause of sleeplessness during pandemics. The relevance of developing measures for rehabilitating patients, particularly use of Sonnovan to restore normal sleep, which plays a fundamental role in supporting people’s mental and physical health, is emphasized.
AbstractList Studies of the neurological symptoms and signs associated with the acute and late phases of infectious diseases are important in pandemic conditions. The novel coronavirus infection (COVID-19) pandemic has increased the number of patients with sleeplessness, this being an adverse prognostic factor for infections. This review addresses the factors and mechanisms of sleep impairments and their relationship with inflammation and immune system dysfunction in infectious diseases. In particular, impairments to the functioning of the melatoninergic system are discussed as the cause of sleeplessness during pandemics. The relevance of developing measures for rehabilitating patients, particularly use of Sonnovan to restore normal sleep, which plays a fundamental role in supporting people’s mental and physical health, is emphasized.
Author Shuldyakov, A. A.
Yudina, V. V.
Runnova, A. E.
Salina, E. A.
Kolokolov, O. V.
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  fullname: Salina, E. A.
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Issue 3
Keywords COVID-19
anxiety
sleep impairments
infection
SARS-CoV-2
sleeplessness
depression
melatonin
Sonnovan
pandemics
Language English
License Springer Nature Switzerland AG 2022.
This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
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SubjectTerms Behavioral Sciences
Biomedical and Life Sciences
Biomedicine
Coronaviruses
COVID-19
Immune system
Infectious diseases
Neurobiology
Neurological diseases
Neurosciences
Pandemics
Sleep
Sleep disorders
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