Cystic Fibrosis–Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes

• Published in: Diabetes care Vol. 46; no. 6; pp. 1112 - 1123
• Main Authors: Putman, Melissa S., Norris, Andrew W., Hull, Rebecca L., Rickels, Michael R., Sussel, Lori, Blackman, Scott M., Chan, Christine L., Ode, Katie Larson, Daley, Tanicia, Stecenko, Arlene A., Moran, Antoinette, Helmick, Meagan J., Cray, Sharon, Alvarez, Jessica A., Stallings, Virginia A., Tuggle, Katherine L., Clancy, John P., Eggerman, Thomas L., Engelhardt, John F., Kelly, Andrea
• Format: Journal Article
• Language: English
• Published: United States American Diabetes Association 01.06.2023
• Subjects: Adolescent; Adult; Bicarbonates; Cystic fibrosis; Cystic Fibrosis - complications; Cystic Fibrosis Transmembrane Conductance Regulator - genetics; Cystic Fibrosis Transmembrane Conductance Regulator - metabolism; Damage tolerance; Diabetes; Diabetes mellitus; Diabetes Mellitus - diagnosis; Glucose Intolerance - complications; Glucose tolerance; Hereditary diseases; Humans; Insulin; Insulin secretion; Intestine; Kidney diseases; Large intestine; Male; Medical diagnosis; Modulators; Morbidity; Pancreas; Pathogenesis; Reproductive system; s in Care; Water balance; Workshops
• ISSN: 0149-5992; 1935-5548; 1935-5548
• DOI: 10.2337/dc23-0380

Cystic fibrosis (CF) is a recessive disorder arising from mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein. CFTR is expressed in numerous tissues, with high expression in the airways, small and large intestine, pancreatic and hepatobiliary ducts,...