Contribution of Bone Marrow–Derived Mesenchymal Stem Cells to Healing of Pulmonary Contusion-Created Rats

• Published in: The Journal of surgical research Vol. 261; pp. 205 - 214
• Main Authors: Demir, Sabri, Erturk, Ahmet, Gunal, Yasemin Dere, Ozmen, Ismail, Zengin, Mehmet, Yildiz, Dincer, Karaoz, Erdal, Karahan, Siyami, Senel, Emrah
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.05.2021
• Subjects: Acute Lung Injury - pathology; Acute Lung Injury - therapy; Animals; Bone Marrow Transplantation; Bone marrow-derived mesenchymal stem cells; Cells, Cultured; Children; Contusions - therapy; Lung - pathology; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells - cytology; Microscopy, Fluorescence; Pulmonary contusion; Rats; Rats, Wistar; Thoracic injury; Trauma; Wound Healing; Thoracic injury; Bone marrow-derived mesenchymal stem cells; Children; Pulmonary contusion; Trauma

The most common thoracic injury in children, resulting in trauma, is pulmonary contusion (PC). Bone marrow–derived mesenchymal stem cells (BM-MSCs) are used in wound healing and many other diseases. This study aims to examine the effects of BM-MSCs on PC healing in rats. A total of 45 male Wistar al...