Assessment of Serum and Urine Neurophil Gelatinase- Associated Lipocalin (s-NGAL and u-NGAL) Level as a Predictive Factor of Disease Progression in Diabetic Nephropathy in Type 2 DM

• Published in: Iranian journal of kidney diseases Vol. 15; no. 4; p. 270
• Main Authors: Najafi, Laily, Keshtkar Rajabi, Shahin, Pirsaheb, Sondos, Keyvani, Hossein, Khajavi, Alireza, Shati, Mohsen, Hadavand, Fahimeh, Amouzegar, Atefeh
• Format: Journal Article
• Language: English
• Published: Tehran Iranian Society of Nephrology 01.07.2021
• Subjects: Biomarkers; Creatinine; Cross-Sectional Studies; Diabetes; Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - diagnosis; Diabetic Nephropathies - diagnosis; Diabetic Nephropathies - etiology; Diabetic nephropathy; Diabetic retinopathy; Disease Progression; Endocrinology; Gelatinases; Humans; Hypertension; Kidney diseases; Lipocalin-2; Lipocalins; Metabolism; Neutrophils; Research centers; Statistical analysis; Systemic diseases; Urine; serum neutrophil gelatinase-associated lipocalin; urine NGAL; microalbuminuria; type II diabetes; macroalbuminuria; diabetic nephropathy

Diabetic nephropathy (DN) is a major complication of diabetes Mellitus. Early detection and intervention of DN can slow its progression and improve patients' outcomes. Neutrophil gelatinase-associated lipocalin (NGAL) as a marker of tubular damage might become a useful biomarker for the evaluat...