IL-15 Trans -Presentation Is an Autonomous, Antigen-Independent Process

Abstract IL-15 plays a pivotal role in the long-term survival of T cells and immunological memory. Its receptor consists of three subunits (IL-15Rα, IL-2/15Rβ, and γc). IL-15 functions mainly via trans-presentation (TP), during which an APC expressing IL-15 bound to IL-15Rα presents the ligand to th...

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Bibliographic Details
Published in	The Journal of immunology (1950) Vol. 207; no. 10; pp. 2489 - 2500
Main Authors	Kenesei, Ádám, Volkó, Julianna, Szalóki, Nikoletta, Mocsár, Gábor, Jambrovics, Károly, Balajthy, Zoltán, Bodnár, Andrea, Tóth, Katalin, Waldmann, Thomas A., Vámosi, György
Format	Journal Article
Language	English
Published	15.11.2021
Online Access	Get full text

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