COVID-19 vaccine effectiveness against hospitalizations in Paraguay, May 2021—April 2022: A test-negative design

• Published in: Vaccine Vol. 41; no. 43; pp. 6453 - 6460
• Main Authors: Irala, Sandra, Hamid, Sarah, Penayo, Elena, Michel, Fabiana, Couto, Paula, Vazquez, Cynthia, Ortega, María José, Domínguez, Chavely, Battaglia, Silvia, Von Horoch, Marta, Montoya, Romeo, Sequera, Guillermo, Nogareda, Francisco
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 13.10.2023; Elsevier Limited
• Subjects: Clinical trials; Comorbidity; COVID-19; COVID-19 vaccines; Effectiveness; Estimates; Hospitals; Illnesses; Immunization; Infections; Medical personnel; mRNA; mRNA vaccines; Paraguay; Patients; Population; Population characteristics; Respiratory tract infection; Severe acute respiratory syndrome coronavirus 2; Surveillance; Vaccination; Vaccine effectiveness; Vaccine efficacy; Vaccines; Beijing China; Paraguay; North America; Europe; China; Latin America; COVID-19; Paraguay; Vaccination; Vaccine effectiveness

•Paraguay’s COVID-19 vaccination campaign used several vaccine platforms.•Surveillance data were used to estimate COVID-19 vaccine effectiveness.•In Paraguay, mRNA vaccines provided better protection than other vaccines against all variants.•The effectiveness of all vaccines declined during the Omic...