Pharmacokinetics of temozolomide in association with fotemustine in malignant melanoma and malignant glioma patients: comparison of oral, intravenous, and hepatic intra-arterial administration - Marzolini, Catia; Shen, Fei; Bauer, Jean; Buclin, Thierry; Biollaz, J r me; Decosterd, Laurent A.; Lejeune, Ferdy; Gander, Marc; Leyvraz, Serge (Cancer chemotherapy and pharmacology, 1998)
Keywords: Administration, Oral; Adult; Aged; Antineoplastic agents; Antineoplastic Combined Chemotherapy Protocols - administration & dosage; Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Biological and medical sciences; Blood-Brain Barrier; Brain Neoplasms - drug therapy; Chemotherapy; Dacarbazine - administration & dosage; Dacarbazine - adverse effects; Dacarbazine - analogs & derivatives; Dacarbazine - cerebrospinal fluid; Female; Glioma - drug therapy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Medical sciences; Melanoma - drug therapy; Middle Aged; Nitrosourea Compounds - administration & dosage; Organophosphorus Compounds - administration & dosage; Pharmacology. Drug treatments; Antineoplastic agent; Human; Urine; Biological fluid; Plasma; Intrahepatic administration; Nervous system diseases; Drug combination; Intravenous administration; Toxicity; Oral administration; Tolerance; Malignant tumor; Bioavailability; Fotemustine; Blood; Malignant glioma; Chemotherapy; Treatment; Central nervous system disease; Malignant melanoma; Temozolomide; Pharmacokinetics