Treatment with AICAR inhibits blastocyst development, trophectoderm differentiation and tight junction formation and function in mice - Calder, Michele D; Edwards, Nicole A; Betts, Dean H; Watson, Andrew J (Molecular human reproduction, 2017)
Keywords: Adenosine Triphosphate - biosynthesis; Aminoimidazole Carboxamide - analogs & derivatives; Aminoimidazole Carboxamide - pharmacology; AMP-Activated Protein Kinases - genetics; AMP-Activated Protein Kinases - metabolism; Animals; Blastocyst - drug effects; Blastocyst - metabolism; Blastocyst - ultrastructure; CDX2 Transcription Factor - genetics; CDX2 Transcription Factor - metabolism; Cell Differentiation - drug effects; Dose-Response Relationship, Drug; Embryo Culture Techniques; Embryonic Development - drug effects; Female; Gene Expression Regulation, Developmental - drug effects; Hypoglycemic Agents - pharmacology; Mice; Original Research; Oxazines - pharmacology; Phosphorylation - drug effects; Ribonucleotides - pharmacology; Signal Transduction; Tight Junctions - drug effects; Tight Junctions - metabolism; Tight Junctions - ultrastructure; AMPK; preimplantation; assisted reproductive technologies; blastocyst formation; embryo culture; stress pathways