Simultaneous Determination of Methanol, Ethanol and Formic Acid in Serum and Urine by Headspace GC-FID

• Published in: Journal of analytical toxicology Vol. 39; no. 9; pp. 741 - 745
• Main Authors: Bursová, Miroslava, Hložek, Tomáš, Čabala, Radomír
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.11.2015
• Subjects: Calibration; Chromatography, Gas; Ethanol - blood; Ethanol - urine; Female; Flame Ionization; Formates - blood; Formates - urine; Humans; Male; Methanol - blood; Methanol - urine

A simple, cost-effective headspace gas chromatography (GC) method coupled with GC with flame ionization detection for simultaneous determination of methanol, ethanol and formic acid was developed and validated for clinical and toxicological purposes. Formic acid was derivatized with an excess of iso...