Clinical evidence of intestinal absorption of Gastrografin

Experimental evidence suggests that Gastrografin in the neonatal gastrointestinal tract leads to hypertonic dehydration by two mechanisms: loss of water from the circulating blood volume, and absorption of osmolarly active substances across intact, normal mucosa of the gastrointestinal tract. Clinic...

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Bibliographic Details
Published inRadiology Vol. 118; no. 1; p. 151
Main Authors Poole, C A, Rowe, M I
Format Journal Article
LanguageEnglish
Published United States 01.01.1976
Subjects
Diatrizoate - analogs & derivatives
Diatrizoate - metabolism
Diatrizoate Meglumine - metabolism
Humans
Infant, Newborn
Infant, Newborn, Diseases - diagnostic imaging
Intestinal Absorption
Intestinal Obstruction - diagnostic imaging
Kidney - diagnostic imaging
Meconium
Radiography, Abdominal
Urinary Bladder - diagnostic imaging
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Summary:Experimental evidence suggests that Gastrografin in the neonatal gastrointestinal tract leads to hypertonic dehydration by two mechanisms: loss of water from the circulating blood volume, and absorption of osmolarly active substances across intact, normal mucosa of the gastrointestinal tract. Clinical documentation of absorption of Gastrografin is presented. Renal excretion of contrast material was seen following its use in the treatment of meconium ileus.
ISSN:0033-8419
1527-1315
DOI:10.1148/118.1.151