Copper‐Catalyzed Synthesis of O/N‐Alkyl S‐Phenyl Phenylcarbamothioates: An Odorless and Chemo‐selective Chan–Lam Reaction to Construct C−S Bond

• Published in: European journal of organic chemistry Vol. 2022; no. 32
• Main Authors: Wu, Yu−Xi, Wang, Xi, Li, Jing‐Hang, Xiao, Hua‐Qing, Dong, Zhi‐Bing
• Format: Journal Article
• Language: English
• Published: WEINHEIM Wiley 26.08.2022; Wiley Subscription Services, Inc
• Subjects: Boronic Acid; Carbamothioate; Catalysis; Chan–Lam Reaction; Chemical synthesis; Chemistry; Chemistry, Organic; Copper; Functional groups; Physical Sciences; Science & Technology; Selectivity; Substrates; Sulfur; Synthesis; Chan-Lam Reaction; BORONIC ACIDS; THIOLS; Synthesis; ARYLATION; Boronic Acid; Carbamothioate; Catalysis; SULFONYL CHLORIDES

A simple and efficient synthetic method to C−S bonds was established based on the Chan–Lam reaction. A series of O/N‐alkyl S‐phenyl phenylcarbamothioates were obtained in good yields by using odorless O/N‐alkyl phenylthiocarbamates as sulfur sources and commercially available phenylboronic acids as...