Enantioselective Copper‐Catalyzed Formal [2+1] and [4+1] Annulations of Diynes with Ketones via Carbonyl Ylides

• Published in: Angewandte Chemie International Edition Vol. 61; no. 43
• Main Authors: Qi, Lin‐Jun, Li, Cui‐Ting, Huang, Zheng‐Qi, Jiang, Jia‐Tian, Zhu, Xin‐Qi, Lu, Xin, Ye, Long‐Wu
• Format: Journal Article
• Language: English
• Published: WEINHEIM Wiley 24.10.2022; Wiley Subscription Services, Inc
• Edition: International ed. in English
• Subjects: Alkynes; Annulation; Asymmetric Catalysis; Asymmetry; Carbenes; Carbonyl compounds; Carbonyl Ylides; Carbonyls; Catalysts; Cations; Chemistry; Chemistry, Multidisciplinary; Copper; Divergence; Enantiomers; Epoxidation; Heterocycles; Ketones; Physical Sciences; Science & Technology; Heterocycles; CARBENOIDS; REACTIVITY; ALDEHYDES; EPOXIDATION; CYCLOADDITION; EPOXIDES; YNAMIDES; Asymmetric Catalysis; Carbonyl Ylides; GENERATION; Annulation; ACCESS; Alkynes; DIHYDROFURANS

Carbonyl ylides have proven to be powerful synthons for the efficient construction of various valuable O‐heterocycles, and the formation of carbonyl ylides by the reaction of metal carbenes with carbonyls has attracted increasing attention over the past decades. However, a catalyst‐controlled highly...